Paraneoplastic Chronic Inflammatory Demyelinating Polyradiculoneuropathy Associated with Renal Cell Carcinoma – A Rare but Critical Diagnosis

Chronic inflammatory demyelinating polyradiculoneuropathy (CIDP) in the context of renal cell carcinoma (RCC) is a rare occurrence. A 73year old male presented with 6 months history of progressive weakness, was diagnosed as CIDP. His condition deteriorated despite treatment, leading to quadriplegia. Further evaluation with imaging revealed a left sided RCC. Following radical nephrectomy, the patient experienced substantial sensory and motor function improvement. This case highlights a rare paraneoplastic link between CIDP and RCC, emphasizing the importance of considering paraneoplastic syndromes in patients with atypical or treatment-resistant neurological conditions. Early recognition and management of the underlying malignancy can significantly improve neurological outcomes.